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Showing posts with label Cell Biology. Show all posts
Showing posts with label Cell Biology. Show all posts

The Dictionary of Cell and Molecular Biology Fourth Edition

The Dictionary of Cell and Molecular Biology Fourth Edition

The Dictionary of Cell and Molecular Biology Fourth Edition
Academic Press| 0123739861 | Edition - 2007-10-22 | PDF | 472 pages | 8 MB

The over 10,000 entries in this comprehensive Dictionary of Cell and Molecular Biology provide clear and concise definitions for anyone working in life sciences today. It incorporates related terms from neuroscience, genetics, microbiology, immunology, pathology, and physiology. This fourth revised edition reflects the enormous changes brought about by the explosion of new technologies, especially high throughput approaches and functional genomics. As a result, this edition is over 30% larger than the previous edition, with 3400 new entries. As with the prior edition, additions are reflective of online search queries performed by users of the dictionary. The entries in this authoritative work have been widely praised for their clarity, brevity, and accuracy throughout. The Dictionary of Cell and Molecular Biology features numerous tables and other useful features.

* Thoroughly revised and expanded by over 30% with 3400 new entries
* Expanded coverage of areas greatly impacted by genomics
* Includes new terms that relate to the recent elucidation of underlying mechanisms of cell cycle regulation, apoptosis, relationship between mitochondria and disease, metabolic control, and stem cell biology
* Consistently provides the most complete short definitions of technical terminology for anyone working in life sciences today
* Extensively cross-referenced
* Provides multiple definitions, notes on word origins, and other useful features

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Molecular Biology of the Cell, Fourth Edition

Molecular Biology of the Cell, Fourth Edition
by Bruce Alberts (Author), Alexander Johnson (Author), Julian Lewis (Author), Martin Raff (Author), Keith Roberts (Author), Peter Walter (Author)
Molecular Biology of the Cell, Fourth Edition
Molecular Biology of the Cell is the classic in-depth text reference in cell biology. By extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and create a coherent framework through which non-expert readers may approach the subject. Written in clear and concise language, and beautifully illustrated, the book is enjoyable to read, and it provides a clear sense of the excitement of modern biology. Molecular Biology of the Cell sets forth the current understanding of cell biology (completely updated as of Autumn 2001), and it explores the intriguing implications and possibilities of the great deal that remains unknown.
The hallmark features of previous editions continue in the Fourth Edition. The book is designed with a clean and open, single-column layout. The art program maintains a completely consistent format and style, and includes over 1,600 photographs, electron micrographs, and original drawings by the authors. Clear and concise concept headings introduce each section. Every chapter contains extensive references. Most important, every chapter has been subjected to a rigorous, collaborative revision process where, in addition to incorporating comments from expert reviewers, each co-author reads and reviews the other authors' prose. The result is a truly integrated work with a single authorial voice

  • Hardcover: 1616 pages
  • Publisher: Garland; 4 edition (March 2002)
  • Language: English
  • ISBN-10: 0815332181
  • ISBN-13: 978-081533218

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Cell Illustrator Pro v3.0 01.30.2007

Cell Illustrator Pro v3.0 01.30.2007
333 magnify
Cell Illustrator Pro v3.0.01.30.2007
Windows + MACOSX + Linux

Cell Illustrator is a software tool that enables biologists to draw, model, elucidate and simulate complex biological processes and systems. It has outstanding drawing capabilities, moreover it allows researchers to model metabolic pathways, signal transduction cascades, gene regulatory pathways as well as dynamic interactions of various biological entities such as genomic DNA, mRNA and proteins.

Cell Illustrator models are used to visualize biopathways, interpret experimental data and test hypotheses. In addition, it provides researchers with model diagrams of publication quality and simulation result charts.

Cell Illustrator provides biochemists with comprehensive visual representations of biochemical processes which form large and complex networks. The software gives new insight to understanding these networks and relationships between chemical components in structurally complex dynamic interactions and processes.

Cell Illustrator aids researchers in modeling metabolic pathways, signal transduction cascades, gene regulatory pathways as well as dynamic interactions of various biological entities such as genomic DNA, mRNA and proteins.

Cell Illustrator has been successfully used to model: gene regulation of the lac operon, Circadian Rhythms in Drosophila melanogaster, Apoptosis Induced by Fas ligand, and the switching mechanism of λ phage.

Easy-to-use Petri Net design methodology and intuitive interface make the Cell Illustrator software an excellent tool for biologist, biochemists, and scientists conducting research in life sciences as well as for graduate educators.

Using Cell Illustration requires no advanced knowledge of differential equations and/or higher mathematics.

Biological pathways modeled with the Cell Illustrator can be visualized and animated using Cell Animator™.

Key Features

* Easy and intuitive User Interface
* SVG Library of biological elements
* All model’s variables and parameters of processes and connectors are tabulated and are easy to modify
* Variables’ actual values can be displayed during simulation
* Five simulation modes: three different continuous simulation modes, step simulation and step simulation with animation
* Discrete processes have unique animated simulation option to observe quantities flow through the system
* Simulation results can be presented on real-time graphs or exported to common format files
* A simulation run can be saved in a log file and replayed in Cell Illustrator Player
* The Simulation History dialog provides access to previous versions of a model and simulation results
* Final simulation results can be presented using Cell Animator with graphs and animations. Sample verified biochemical models created using Cell Illustrator are available
* Import of SBML and CellML models
* Special visualization mode dedicated for the analysis of Gene Relationship Networks

Cell Illustrator can be used for:
Easy construction and visualization of biological pathways and processes
Simulation of systems that include both discrete and continuous processes
Simulation animation
Creating model diagrams of publication quality
Importing models from public or proprietary libraries and databases like KEGG
Analysis and exploration of gene relationship networks

New in This Release 3.0 (latest version)


Import of SBML/CellML files
New input filters allow importing models stored in the widely used CellML and SBML formats. The imported SBML/CellML models are converted to Cell Illustrator models and can be edited, analyzed, simulated or saved as any other Cell Illustrator model. This function converts SBML/CellML models, which use differential equations for representing relationships between entities, to CI models, which use the Petri Net formalism used in CI.

Library of SVG graphical elements
The library of Biological Elements has been extended with SVG images representing biological entities, processes and cellular components. The library consists of: about 40 images for biological entities, more than 250 images for biological processes and about 70 images for cell components.
Each image corresponds to one Gene Ontology (or Cell System Ontology) term. Each image can be edited in the SVG editor included in Cell Illustrator.

Enhancements in the Petri Net simulation engine
New options for a better control of the simulation flow have been added. The weak firing and firing accuracy options available in the Simulation Settings facilitate the simulation of continuous models.

Improved Charts
Charts dialog boxes have been enhanced for improved viewing, analysis and control of simulation results.

External References
Since the version 3.0, Cell Illustrator offers an extensive support for external references to public databases, Gene or Cell Ontology terms, etc. These references can be defined in the new Biological tab of the Element Setting dialog box, as well as in the redesigned External References dialog box. Also, URL Templates can be defined to access public databases. The URLs of the external references can be opened in the web browser.

Gene Network View
The added Gene Network Mode enables the user to view and explore gene relationships networks. This mode offers a special visualization style and tools for the analysis of gene relationship networks, such as Pathway Search, Sub-network Extraction and Network Merge.

More Information :

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Cell Illustrator Pro v3.0 01.30.2007

Cell Illustrator Pro v3.0 01.30.2007
333 magnify
Cell Illustrator Pro v3.0.01.30.2007
Windows + MACOSX + Linux

Cell Illustrator is a software tool that enables biologists to draw, model, elucidate and simulate complex biological processes and systems. It has outstanding drawing capabilities, moreover it allows researchers to model metabolic pathways, signal transduction cascades, gene regulatory pathways as well as dynamic interactions of various biological entities such as genomic DNA, mRNA and proteins.

Cell Illustrator models are used to visualize biopathways, interpret experimental data and test hypotheses. In addition, it provides researchers with model diagrams of publication quality and simulation result charts.

Cell Illustrator provides biochemists with comprehensive visual representations of biochemical processes which form large and complex networks. The software gives new insight to understanding these networks and relationships between chemical components in structurally complex dynamic interactions and processes.

Cell Illustrator aids researchers in modeling metabolic pathways, signal transduction cascades, gene regulatory pathways as well as dynamic interactions of various biological entities such as genomic DNA, mRNA and proteins.

Cell Illustrator has been successfully used to model: gene regulation of the lac operon, Circadian Rhythms in Drosophila melanogaster, Apoptosis Induced by Fas ligand, and the switching mechanism of λ phage.

Easy-to-use Petri Net design methodology and intuitive interface make the Cell Illustrator software an excellent tool for biologist, biochemists, and scientists conducting research in life sciences as well as for graduate educators.

Using Cell Illustration requires no advanced knowledge of differential equations and/or higher mathematics.

Biological pathways modeled with the Cell Illustrator can be visualized and animated using Cell Animator™.

Key Features

* Easy and intuitive User Interface
* SVG Library of biological elements
* All model’s variables and parameters of processes and connectors are tabulated and are easy to modify
* Variables’ actual values can be displayed during simulation
* Five simulation modes: three different continuous simulation modes, step simulation and step simulation with animation
* Discrete processes have unique animated simulation option to observe quantities flow through the system
* Simulation results can be presented on real-time graphs or exported to common format files
* A simulation run can be saved in a log file and replayed in Cell Illustrator Player
* The Simulation History dialog provides access to previous versions of a model and simulation results
* Final simulation results can be presented using Cell Animator with graphs and animations. Sample verified biochemical models created using Cell Illustrator are available
* Import of SBML and CellML models
* Special visualization mode dedicated for the analysis of Gene Relationship Networks

Cell Illustrator can be used for:
Easy construction and visualization of biological pathways and processes
Simulation of systems that include both discrete and continuous processes
Simulation animation
Creating model diagrams of publication quality
Importing models from public or proprietary libraries and databases like KEGG
Analysis and exploration of gene relationship networks

New in This Release 3.0 (latest version)


Import of SBML/CellML files
New input filters allow importing models stored in the widely used CellML and SBML formats. The imported SBML/CellML models are converted to Cell Illustrator models and can be edited, analyzed, simulated or saved as any other Cell Illustrator model. This function converts SBML/CellML models, which use differential equations for representing relationships between entities, to CI models, which use the Petri Net formalism used in CI.

Library of SVG graphical elements
The library of Biological Elements has been extended with SVG images representing biological entities, processes and cellular components. The library consists of: about 40 images for biological entities, more than 250 images for biological processes and about 70 images for cell components.
Each image corresponds to one Gene Ontology (or Cell System Ontology) term. Each image can be edited in the SVG editor included in Cell Illustrator.

Enhancements in the Petri Net simulation engine
New options for a better control of the simulation flow have been added. The weak firing and firing accuracy options available in the Simulation Settings facilitate the simulation of continuous models.

Improved Charts
Charts dialog boxes have been enhanced for improved viewing, analysis and control of simulation results.

External References
Since the version 3.0, Cell Illustrator offers an extensive support for external references to public databases, Gene or Cell Ontology terms, etc. These references can be defined in the new Biological tab of the Element Setting dialog box, as well as in the redesigned External References dialog box. Also, URL Templates can be defined to access public databases. The URLs of the external references can be opened in the web browser.

Gene Network View
The added Gene Network Mode enables the user to view and explore gene relationships networks. This mode offers a special visualization style and tools for the analysis of gene relationship networks, such as Pathway Search, Sub-network Extraction and Network Merge.

More Information :

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System Modeling in Cellular Biology : From Concepts to Nuts and Bolts

System Modeling in Cellular Biology : From Concepts to Nuts and Bolts
Book Publisher: The MIT Press (03 April, 2006)
ISBN: 0262195488
Book author: Zoltan Szallasi, Jörg Stelling, Vipul Periwal
http://mitpress.mit.edu/images/products/books/0262195488-f30.jpg

Book Description:
Research in systems biology requires the collaboration of researchers from diverse backgrounds, including biology, computer science, mathematics, statistics, physics, and biochemistry. These collaborations, necessary because of the enormous breadth of background needed for research in this field, can be hindered by differing understandings of the limitations and applicability of techniques and concerns from different disciplines. This comprehensive introduction and overview of system modeling in biology makes the relevant background material from all pertinent fields accessible to researchers with different backgrounds.
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Nature Reviews Molecular Cell Biology "All issues" - 2000 to 2006


Language: English | PDF - SWF - MOV | approx 700 MB
Nature Reviews Molecular Cell Biology
from its 1st issue to 2006 december
6years, 75 issues including highlights, reviews, perspectives, errata, supplemental videos, figures

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Molecular Cell Biology, Fifth Edition by Harvey Lodish, Arnold Berk et.al

ISBN: 0716743663
Title: Molecular Cell Biology, 5th Edition
Author: Matthew P Scott
Publisher: W. H. Freeman
Publication Date: 2003-08-01Number Of Pages: 973
Molecular Cell Biology, Fifth Edition

by Harvey Lodish, Arnold Berk, S. Lawrence Zipursky, Paul Matsudaira, , James Darnell
W.H. Freeman & Company
Molecular Cell Biology stands out from its peers in this course in that it provides a clear introduction to the techniques and experiments of scientists past and present, not just an \"encyclopedia\" of information. This experimental emphasis, together with a solid pedagogical framework in the chapters, provides the clearest, most cutting-edge text available.

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The Y Chromosome and Male Germ Cell Biology in Health and Diseases

The Y Chromosome and Male Germ Cell Biology in Health and Diseases
World Scientific Publishing Company | 9812703748 | Edition - 2007-04-16 | PDF | 324 pages | 2.56 MB

The completion of the human genome and technological advances developed by the Human Genome Project have dramatically changed our understanding of the mechanisms underlying the development and differentiation of male germ cells, and our ability to investigate such mechanisms. This book is a timely document of advances made in the field of male gonad and germ cell research in the postgenomic era. The coverage includes the role of Y chromosome genes in male reproduction, gene expression in spermatogonial stem cells and male germ cells, and the regulation of germ cell genes in reproduction and in germ cell tumors.
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The Dictionary of Cell and Molecular Biology Fourth Edition

The Dictionary of Cell and Molecular Biology Fourth Edition
Academic Press| 0123739861 | Edition - 2007-10-22 | PDF | 472 pages | 8 MB

The over 10,000 entries in this comprehensive Dictionary of Cell and Molecular Biology provide clear and concise definitions for anyone working in life sciences today. It incorporates related terms from neuroscience, genetics, microbiology, immunology, pathology, and physiology. This fourth revised edition reflects the enormous changes brought about by the explosion of new technologies, especially high throughput approaches and functional genomics. As a result, this edition is over 30% larger than the previous edition, with 3400 new entries. As with the prior edition, additions are reflective of online search queries performed by users of the dictionary. The entries in this authoritative work have been widely praised for their clarity, brevity, and accuracy throughout. The Dictionary of Cell and Molecular Biology features numerous tables and other useful features.

* Thoroughly revised and expanded by over 30% with 3400 new entries
* Expanded coverage of areas greatly impacted by genomics
* Includes new terms that relate to the recent elucidation of underlying mechanisms of cell cycle regulation, apoptosis, relationship between mitochondria and disease, metabolic control, and stem cell biology
* Consistently provides the most complete short definitions of technical terminology for anyone working in life sciences today
* Extensively cross-referenced
* Provides multiple definitions, notes on word origins, and other useful features
Download

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The Y Chromosome and Male Germ Cell Biology in Health and Diseases

The Y Chromosome and Male Germ Cell Biology in Health and Diseases
World Scientific Publishing Company | 9812703748 | Edition - 2007-04-16 | PDF | 324 pages | 2.56 MB

The completion of the human genome and technological advances developed by the Human Genome Project have dramatically changed our understanding of the mechanisms underlying the development and differentiation of male germ cells, and our ability to investigate such mechanisms. This book is a timely document of advances made in the field of male gonad and germ cell research in the postgenomic era. The coverage includes the role of Y chromosome genes in male reproduction, gene expression in spermatogonial stem cells and male germ cells, and the regulation of germ cell genes in reproduction and in germ cell tumors.
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Morphology Methods: Cell and Molecular Biology Techniques

Morphology Methods: Cell and Molecular Biology Techniques
Humana Press| 0896039552 | Edition - 2001-06-15 | PDF | 422 pages| 2.4 MB | Rapidshare &Megaupload

Ricardo Lloyd, md, phd, provides critical and tutorial surveys of the cutting-edge molecular and cell biologic techniques used today in the analysis of cells and tissues in situ. These molecular-based histologic and morphologic techniques are described in step-by-step detail by hands-on experts, often those who have originated or perfected them. Among the techniques presented are laser capture microdissection, in situ hybridization, FISH, confocal laser scanning microscopy, in situ PCR, and tyramide amplification. Applications include the detection of infectious agents and DNA, the diagnosis of undifferentiated tumors and endocrine lesions, the metaphase analysis of whole blood cultures, and clonality analysis. In its integrated, state-of-the-art approach, Morphology Methods: Cell and Molecular Biology Techniques thoroughly details and applies the rich panoply of significant new cell and molecular biologic technologies to all the major problems confronting morphologic studies and diagnostic pathology today.
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Methods in Plant Electron Microscopy and Cytochemistry

Methods in Plant Electron Microscopy and Cytochemistry
Humana Press| 0896038092 | Edition - 2000-06-29 | PDF | 312 pages| 8.8 MB | Rapidshare &Megaupload

Hands-on experimentalists describe the cutting-edge microscopical methods needed for the effective study of plant cell biology today. These powerful techniques, all described in great detail to ensure successful experimental results, range from light microscope cytochemistry, autoradiography, and immunocytochemistry, to recent developments in fluorescence, confocal, and dark-field microscopies. Important advances in both conventional and scanning electron microscopies are also fully developed, together with such state-of-the-art ancillary techniques as high-resolution autoradiography, immunoelectron microscopy, X-ray microanalysis, and electron systems imaging. Easy-to-use and up-to-date, Methods in Plant Electron Microscopy and Cytochemistry offers today's plant scientists a first class collection of readily reproducible light and electron microscopical methods that will prove the new standard for all working in the field.
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Handbook of Industrial Cell Culture: Mammalian, Microbial, and Plant Cells

Handbook of Industrial Cell Culture: Mammalian, Microbial, and Plant Cells
Humana Press| 1588290328 | Edition - 2002-12-06 | PDF | 546 pages| 3.9 MB | Rapidshare & Megaupload

A diverse team of researchers, technologists, and engineers describe, in simple and practical language, the major current and evolving technologies for improving the biocatalytic capabilities of mammalian, microbial, and plant cells. The authors present state-of-the-art techniques, proven methods, and strategies for industrial screening, cultivation, and scale-up of these cells, and describe their biotech and industrial uses. Special emphasis is given to the solving critical issues encountered during the discovery of new drugs, process development, and the manufacture of new and existing compounds. Other topics include recombinant protein expression, bioinformatics, high throughput screening, analytical tools in biotechnology, DNA shuffling, and genomics discovery.
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Zinc Finger Proteins: From Atomic Contact to Cellular Function

Zinc Finger Proteins: From Atomic Contact to Cellular Function
Landes Bioscience | English | ISBN: 1417574476 | 276 pages | 2005 | PDF | 8 Mb

Zinc Finger Proteins is the first book to systematically assemble knowledge of various zinc finger proteins belonging to several families and to describe features of zinc finger proteins at levels ranging from atomic to cellular and to organismal. Significance of zinc itself is also addressed as are important domains often associated with zinc fingers. This book is an ideal resource for students who want to learn about zinc finger proteins as well as for scientists who work on gene expression, signal transduction, differentiation, development, cancer and neurological diseases.

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Cell Biology Protocols-Robin, Ed. Harris

Robin, Ed. Harris, "Cell Biology Protocols "
John Wiley & Sons; 1 edition (2006) | ISBN:0470847581 | 402 pages | PDF | 13 Mb

As a modern composite scientific discipline, Cell Biology has expanded and moved forward rapidly in recent years. Cell Biologists now require a wide range of techniques, including those of analytical biochemistry and microscopy in all its diverse forms. These are often used alongside the techniques of molecular biology and molecular genetics. This book contains numerous useful protocols, covering light and electron microscopy, cell culture, cell separation, subcellular fractionation, organelle and membrane isolation, and the use of in vitro reassembly systems in Cell Biology. Many of these protocols feature helpful notes and safety information for practical application. The format favours easy use at the bench with space for notes and important safety information. An appendix contains essential analytical information that will prove invaluable to those working on all aspects of cell biology.

This book will be of interest to students and more experienced cell biologists, as well as molecular biologists and those working in genomics and proteomics who are looking for cellular techniques to validate their findings within intact cells.
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Gene and Cell Therapy: Therapeutic Mechanisms and Strategies

Gene and Cell Therapy: Therapeutic Mechanisms and Strategies
CRC Press | ISBN: 0824741048 | 2004 | PDF | 875 pages | 13.2 Mb | RS

This reference is completely revised and expanded to reflect the most critical studies, controversies, and technologies impacting the medical field, including probing research on lentivirus, gutless adenovirus, bacterial and baculovirus vectors, retargeted viral vectors, in vivo electroporation, in vitro and in vivo gene detection systems, and all inducible gene expression systems. Scrutinizing every tool, technology, and issue impacting the future of gene and cell research, it is specifically written and organized for laymen, scholars, and specialists from varying backgrounds and disciplines to understand the current status of gene and cell therapy and anticipate future developments in the field.
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Cells and Robots - Modeling and Control of Large-Size Agent Populations

Cells and Robots - Modeling and Control of Large-Size Agent Populations
Publisher: Springer | Language: English | ISBN: 3540719814 | 1240pages | Data: 2007 | PDF | 5.1 Mb

Description: Cells and Robots is an outcome of the multidisciplinary research extending over Biology, Robotics and Hybrid Systems Theory. It is inspired by modeling reactive behavior of the immune system cell population, where each cell is considered as an independent agent. In our modeling approach, there is no difference if the cells are naturally or artificially created agents, such as robots. This appears even more evident when we introduce a case study concerning a large-size robotic population scenario. Under this scenario, we also formulate the optimal control of maximizing the probability of robotic presence in a given region and discuss the application of the Minimum Principle for partial differential equations to this problem. Simultaneous consideration of cell and robotic populations is of mutual benefit for Biology and Robotics, as well as for the general understanding of multi-agent system dynamics.
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Artificial cells, cell engineering and therapy

Artificial cells, cell engineering and therapy
Publisher: Woodhead Publishing | Language: English | ISBN:1845690362 | 544 pages | Data: 2007 | PDF | 2.8 Mb

Artificial cells, cell engineering and therapy are emerging technologies which will make a significant impact on the future of medicine and healthcare. However, research within the field is vast. This unique book provides a comprehensive study of the most recent advances in the field and its practical applications.

The first part of the book offers the reader an introduction to the basics of artificial cell technology with chapters on its origins, design, current status within medicine and future prospects. Part 2 covers apoptosis, the use of bone marrow stromal cells in myocardial regeneration together with signalling and tissue engineering. Part 3 discusses artificial cells for therapy, procedures for various clinical conditions and the current status of the discipline within the field. The book concludes with a final section on the role of artificial cells in medicine with particular focus on the use of artificial cells as blood substitutes and their potential use in myocardial regeneration, drug delivery and in treating kidney and bowel diseases, diabetes and cancer.
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Mechanisms of Lymphocyte Activation and Immune Regulation XI: B Cell Biology

Mechanisms of Lymphocyte Activation and Immune Regulation XI: B Cell Biology
Publisher: Springer | Language: English | ISBN:0387465278 | 208 pages | Data: 2007 | PDF | 2.3 Mb
Description: In recent years, major developments have been made in understanding various genetic and epigenetic regulatory processes that are critical for the generation of B cell repertoires. These include the role of chromatin regulation and nuclear organization in understating the IgH gene regulation. A role and mechanism of DNA repair proteins in somatic hypermutation has been elucidated. Genetic mutation studies have been instrumental in providing insight into some of the mechanisms involved in targeting CSR to various switch DNA regions located upstream of C region genes, especially a role of AID motifs, transcription, and R-loops. Recent studies support a dominant role of receptor editing in central B cell tolerance and signaling pathways that regulate receptor editing in self-reactive and non-self-reactive immature B cells. These were some of the topics of discussion at the 11th International Conference on B cell Biology. These proceedings highlight recent developments in lymphocyte development, Ig gene rearrangements and somatic hypermutation, chromatin structure modification, B lymphocyte signaling and fate, receptor editing, and autoimmunity.
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Handbook of Cell Signaling, Three-Volume Set

Handbook of Cell Signaling, Three-Volume Set

Publisher: Academic Press | Language: English | ISBN: 0121245462 | 2576 pages | Data: 2003 | PDF | 32 Mb
Description: The Handbook of Cell Signaling is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses.

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