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In Computational Neuroanatomy: Principles and Methods, the path-breaking investigators who founded the field review the principles and key techniques available to begin the creation of anatomically accurate and complete models of the brain. Combining the vast, data-rich field of anatomy with the computational power of novel hardware, software, and computer graphics, these pioneering investigators lead the reader from the subcellular details of dendritic branching and firing to system-level assemblies and models. A companion CD-ROM includes software used in computational neuroanatomy, sample data files animations of the results reported in the book, high-resolution color illustrations, and links to useful websites.
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Proteomics is a systematic approach for studying the identity and function of all proteins expressed in a cell, tissue or organ. New drug targets for diseases are often identified by comparing the proteome of the disease state to the normal state. As a result, proteomics has become increasingly important in the pharmaceutical and biotechnology industries as well as academics. This book contains five sections encompassing the research aspects of proteomics on the brain including the most recent advances in the technology and informatics. It discusses advances in high-throughput proteomic technologies and their application to studying neurological disorders such as Alzheimers disease, alcoholism, trauma/stroke, Huntington's disease, and Parkinson's disease. With numerous illustrations to explain the concepts, it provides a comprehensive review on the topic.
* Describes the latest databases and techniques for analyzing the data generated by proteomics
* Outlines the latest developments in proteomic methods
* Provides numerous color illustrations highlighting the application of proteomics to the identification of novel drug targets and biomarkers

This monograph examines the role of the Müller cell, the main glial element of the retina, in the development, organization, and function of the vertebrate retina. These cells may also play a role in the control of eye growth and in determining the processing of information by surrounding neurons.